John Hollins has a full-strength squad to select from as his side welcome Cambridge United to the Vetch Field.
With the Swans already relegated to Division Three, Hollins may decide to ring the changes in order to give some of his beleaguered side a weekend off.
The Welsh side took out their frustration against Brentford on Tuesday as they hammered the visitors 6-0, but Hollins is unlikely to stick with the same squad and may give some of his fringe players a run out.
Midfielders Stuart Roberts and Gareth Phillips are in line to be promoted from the bench after impressing as substitutes in the Brentford clash, while youngster Andrew Mumford could also be given his chance.
Cambridge manager John Beck has no new injury or suspension concerns ahead of his side's final game of the season, but he may give some of his younger players a run-out.
The Us travel to South Wales safe in the knowledge that their Division Two status is preserved for another season after Bristol Rovers' defeat by Wycombe in midweek.
Tom Youngs will again be forced to miss out because of an ankle injury and Beck admits that could leave the door open for his up-and-coming stars.
He said: "I'm very pleased that we are safe but we'll treat this match like we treat every game. Now we are safe we might give some of the kids a go."
Hollins said he wants his side to build on their superb 6-0 victory over Brentford with another win as he looks ahead to next week's FAW Premier Cup semi-finals.
"We have got to make sure we carry on and keep the momentum going with the first leg against Merthyr coming on Tuesday," he said.
"I'm not desperate for next season to start. "We've got to finish this one first and hopefully we can pick up a trophy in the process. "It would be nice to take something out of this season."
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