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Corona Virus 22:39 - Mar 7 with 424819 viewsSgorioFruit

Sorry for new thread,
But how bad do you lot reckon it’s going to get here in the UK?
I just been watching the news. Looking nasty in Italy.

My methods are not favoured by some but by god i speak the truth.
Poll: What Happened Today???

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Corona Virus on 19:27 - Apr 16 with 1817 viewsmonmouth

Corona Virus on 19:25 - Apr 16 by exiledclaseboy

Are you me?


Possibly. Do you look like Steve Martin in Roxanne?

Poll: TRUST MEMBERS: What DID you vote in the, um, vote

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Corona Virus on 19:28 - Apr 16 with 1807 viewsexiledclaseboy

Corona Virus on 19:27 - Apr 16 by monmouth

Possibly. Do you look like Steve Martin in Roxanne?


No. Think Fred Elliott in Coronation Street.

Poll: Tory leader

1
Corona Virus on 19:30 - Apr 16 with 1800 viewssainthelens

Corona Virus on 19:27 - Apr 16 by monmouth

Possibly. Do you look like Steve Martin in Roxanne?


Please say Ruprect in Dirty Rotten Scoundrels.
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Corona Virus on 19:30 - Apr 16 with 1795 viewsmonmouth

Corona Virus on 19:28 - Apr 16 by exiledclaseboy

No. Think Fred Elliott in Coronation Street.


I’m going to have to look that up. I have a feeling it’ll improve my mood.

Edit. It did.
[Post edited 16 Apr 2020 19:31]

Poll: TRUST MEMBERS: What DID you vote in the, um, vote

1
Corona Virus on 21:00 - Apr 16 with 1722 viewswaynekerr55

Corona Virus on 19:28 - Apr 16 by exiledclaseboy

No. Think Fred Elliott in Coronation Street.


Ffs Clasey

How many of you know what DP stands for?
Poll: POTY 2019
Blog: Too many things for a title, but stop with the xenophobia accusations!

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Corona Virus on 22:09 - Apr 16 with 1653 viewsOldjack

Corona Virus on 18:20 - Apr 16 by raynor94

Do you really care about football at this time?


this is a football board ,tit

Prosser the Tosser dwells on Phil's bum hole like a rusty old hemorrhoid ,fact You Greedy Bastards Get Out Of OUR Club!

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Corona Virus on 22:35 - Apr 16 with 1607 viewsGaryjack

Corona Virus on 22:09 - Apr 16 by Oldjack

this is a football board ,tit


Yes, but this is a thread about a virus that is killing thousands upon thousands of people worldwide, and your contribution is "The football will be fvcked"!
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Corona Virus on 22:44 - Apr 16 with 1596 viewsraynor94

Corona Virus on 22:09 - Apr 16 by Oldjack

this is a football board ,tit


Genuinely speechless

You give it out, you take it back it`s all part of the game
Poll: Happy to see Martin go

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Corona Virus on 23:12 - Apr 16 with 1564 viewsmajorraglan

PHW did 755 tests yesterday, they have a capacity of 1300 but we should have been at 5,000 by me. Dreadful.
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Corona Virus on 23:28 - Apr 16 with 1537 viewsJoe_bradshaw

Corona Virus on 22:09 - Apr 16 by Oldjack

this is a football board ,tit


It's on the non football board ya big booby.

Planet Swans Prediction League Winner Season 2013-14. Runner up 2014_15.
Poll: How many points clear of relegation will we be on Saturday night?

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Corona Virus on 00:49 - Apr 17 with 1482 viewslonglostjack

Corona Virus on 10:20 - Apr 16 by Professor

There are multiple genetic factors and epigenetic factors at play. The most obvious one is distribution of the differing ACE2 receptor types that the virus targets for cell entry. Typically this is a weak point of any virus in the need for a specific type of receptor which means that a population or ethnic group that may have a greater or lesser amount of the specific receptor that SARs-CoV2 uses. The specificity also means that viruses rarely species 'jump'.

Secondly there will be a big immunogenetics component based on a molecule called MHC. MHC Class I molecules are on most cells and allow the immune system to recognise if a cell in cancerous or infected. Class II are on specialised cells which present antigen to receptors on host lymphocytes which lead to the generation of antibody responses. We each have 6 different class I and II molecules. The right MHC type is needed to effectively deal with a pathogen-if you have the right one in your armoury you get a better immune response. As each molecule is polymorphic we can deal with many infections (personal survival) but variation in the types in a population lead to at least some of the population being effective against any individual challenge. There will be masses of other variations in the immune system ranging on how effective cells like macrophages are at killing the virus, how well we regulate inflammation and so on.

There are also non-immune factors e.g. sickle cell trait which gives more resistance to malaria, and perhaps even vitamin D (though seems unlikely) but lifestyle factors lead to non-genetic changes or epigenetic changes that can lead to marked differences in resistance-e.g. exposure to pollution, a specific diet components. I am not talking of obesity and other obvious factors, but subtle changes we don't easily see


ACE2 Receptors. What’s your take on blood pressure medication Prof?

Poll: Alcohol in the lockdown

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Corona Virus on 00:53 - Apr 17 with 1479 viewslonglostjack

Corona Virus on 19:24 - Apr 16 by monmouth

Snap. My life is much the same, and I don’t have to feel any unease for not having any friends. As long as I can get food and beer and work remotely to get the money to pay for the quantity of beer I need, I can do lockdown until hell freezes over.

Or strictly come dancing is allowed back on.


Bang on!

Poll: Alcohol in the lockdown

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Corona Virus on 06:12 - Apr 17 with 1402 viewsJACKMANANDBOY

Nervtag minutes

https://m.box.com/shared_item/https%3A%2F%2Fapp.box.com%2Fs%2F3lkcbxepqixkg4mv64

Show virus only rated moderate risk at end of Feb by UK scientists.

Besian Idrizaj Forever a Jack
Poll: When will Duff Revert to 4 at the Back

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Corona Virus on 07:24 - Apr 17 with 1366 viewsHighjack

That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room?

The creatures outside looked from pig to man, and from man to pig, and from pig to man again; but already it was impossible to say which was which.
Poll: Should Dippy Drakeford do us all a massive favour and just bog off?

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Corona Virus on 07:45 - Apr 17 with 1353 viewsJACKMANANDBOY

Corona Virus on 07:24 - Apr 17 by Highjack

That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room?


Let's see how many he can source. WHO says masks should be reserved for health workers.
[Post edited 17 Apr 2020 7:50]

Besian Idrizaj Forever a Jack
Poll: When will Duff Revert to 4 at the Back

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Corona Virus on 07:51 - Apr 17 with 1346 viewsKilkennyjack

Corona Virus on 07:24 - Apr 17 by Highjack

That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room?


No - good spot. I suspect Mr Khan knows more about attacking football though.

Obviously Mr Khan is correct about the masks.
The only reason for any other guidance would be to protect supply lines for the medical workers. And thats fair enough.

In Tesco Fforestfach this week about 20% of people were wearing masks anyhow...?

Beware of the Risen People

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Corona Virus on 07:55 - Apr 17 with 1339 viewsHighjack

Corona Virus on 07:51 - Apr 17 by Kilkennyjack

No - good spot. I suspect Mr Khan knows more about attacking football though.

Obviously Mr Khan is correct about the masks.
The only reason for any other guidance would be to protect supply lines for the medical workers. And thats fair enough.

In Tesco Fforestfach this week about 20% of people were wearing masks anyhow...?


Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them.

Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something?

The creatures outside looked from pig to man, and from man to pig, and from pig to man again; but already it was impossible to say which was which.
Poll: Should Dippy Drakeford do us all a massive favour and just bog off?

0
Corona Virus on 08:21 - Apr 17 with 1323 viewsJACKMANANDBOY

Corona Virus on 07:55 - Apr 17 by Highjack

Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them.

Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something?


Looks like Tesco stores in Fforestfach
[Post edited 17 Apr 2020 8:21]

Besian Idrizaj Forever a Jack
Poll: When will Duff Revert to 4 at the Back

1
Corona Virus on 09:03 - Apr 17 with 1280 viewsOldjack

Corona Virus on 23:28 - Apr 16 by Joe_bradshaw

It's on the non football board ya big booby.


99% of people who visit this SITE are football fans

Prosser the Tosser dwells on Phil's bum hole like a rusty old hemorrhoid ,fact You Greedy Bastards Get Out Of OUR Club!

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Corona Virus on 09:42 - Apr 17 with 1251 viewsJACKMANANDBOY

Corona Virus on 09:03 - Apr 17 by Oldjack

99% of people who visit this SITE are football fans


The other 1 percent I'm worried about.

Besian Idrizaj Forever a Jack
Poll: When will Duff Revert to 4 at the Back

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Corona Virus on 10:12 - Apr 17 with 1223 viewschad

Corona Virus on 07:55 - Apr 17 by Highjack

Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them.

Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something?


Possibly NHS advice is based on WHO advice, which itself to me seemed primarily aimed at protecting supplies to the health service.

WHO of course in mid jan notably also advised no reason for travel restrictions with China or checks on travellers; and at much the same time gave validity to the report from China saying there was no evidence of human to human transmission by tweeting it. This at a time when China was already imprisoning doctors who were trying to alert others to the dangers of infection by this virus after witnessing it themselves.

WHO also only recommend a 1 metre social distance when it is well recognised that coughs and sneezes can travel much much further and create aerosols (as shown with photographic evidence in research by MIT.). As well as the potential for aerosol transmission (as per measles and several others) when it has been shown that the virus can remain infectiously viable in aerosols for at least 3 hours.


Ordinary face masks (Fluid Resistant Surgical Masks) do not protect the eyes and are not fine enough to prevent the virus from entering in aerosol but can prevent the main droplet path and is believed can deflect air flows containing the virus so can afford a degree of protection. Their multilayered construct also affords some protection. Most importantly given the wide spread of this virus, the ability to infect others from the high viral load in the throat which exists at early stages and potential for low / no symptoms at these early stages, then we should welcome others wearing them as they suppress droplets (accepted by WHO as primary cause of transmission) both from coughing/sneezing and talking/breathing


Screwfix used to stock a good selection of disposable and reusable P3 masks (that will stop the virus with a high degree of efficiency if fitted properly) but I understand they (rightfully) diverted all their stocks for care workers when this flared up. But any significant face covering can afford some degree of protection especially against you spreading it.

I have no idea where people are getting their masks from, some will have some from DIY as do I. I know even in the early stages there were reports of thousands being stolen from French hospitals. Our NHS also reportedly had a large order with a French company, as one of their initial clients, but Macron forced them to cancel it when he decided to retain all their masks and mask production for France. My personal opinion, once hospitals, care homes and service providers catered for we need to roll them out widely with strong information about their handling, use and limitations.

I fear however the government are sitting on stocks and trying to promote correct? but prudent use for a reason, the same reason we have all the field hospitals and morgues. They know it could get worse and envisage being left without PPE.

We need to do everything we can to, where possible direct our own resources to production.
[Post edited 17 Apr 2020 10:14]
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Corona Virus on 10:16 - Apr 17 with 1209 viewsProfessor

Corona Virus on 00:49 - Apr 17 by longlostjack

ACE2 Receptors. What’s your take on blood pressure medication Prof?


No idea sorry. There seems to be increased prevalence in metabolic diseases and obesity which could also be related to medication for blood pressure, but that is just speculation on my part. One thing that may come out retrospectively I guess
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Corona Virus on 10:18 - Apr 17 with 1207 viewschad

Corona Virus on 19:28 - Apr 16 by exiledclaseboy

No. Think Fred Elliott in Coronation Street.


‘No. Think Fred Elliott in Coronation Street.’

I said

Think Fred Elliott in Coronation Street.



There fixed that for you ;)
3
Corona Virus on 10:29 - Apr 17 with 1189 viewsBrynmill_Jack

Corona Virus on 10:12 - Apr 17 by chad

Possibly NHS advice is based on WHO advice, which itself to me seemed primarily aimed at protecting supplies to the health service.

WHO of course in mid jan notably also advised no reason for travel restrictions with China or checks on travellers; and at much the same time gave validity to the report from China saying there was no evidence of human to human transmission by tweeting it. This at a time when China was already imprisoning doctors who were trying to alert others to the dangers of infection by this virus after witnessing it themselves.

WHO also only recommend a 1 metre social distance when it is well recognised that coughs and sneezes can travel much much further and create aerosols (as shown with photographic evidence in research by MIT.). As well as the potential for aerosol transmission (as per measles and several others) when it has been shown that the virus can remain infectiously viable in aerosols for at least 3 hours.


Ordinary face masks (Fluid Resistant Surgical Masks) do not protect the eyes and are not fine enough to prevent the virus from entering in aerosol but can prevent the main droplet path and is believed can deflect air flows containing the virus so can afford a degree of protection. Their multilayered construct also affords some protection. Most importantly given the wide spread of this virus, the ability to infect others from the high viral load in the throat which exists at early stages and potential for low / no symptoms at these early stages, then we should welcome others wearing them as they suppress droplets (accepted by WHO as primary cause of transmission) both from coughing/sneezing and talking/breathing


Screwfix used to stock a good selection of disposable and reusable P3 masks (that will stop the virus with a high degree of efficiency if fitted properly) but I understand they (rightfully) diverted all their stocks for care workers when this flared up. But any significant face covering can afford some degree of protection especially against you spreading it.

I have no idea where people are getting their masks from, some will have some from DIY as do I. I know even in the early stages there were reports of thousands being stolen from French hospitals. Our NHS also reportedly had a large order with a French company, as one of their initial clients, but Macron forced them to cancel it when he decided to retain all their masks and mask production for France. My personal opinion, once hospitals, care homes and service providers catered for we need to roll them out widely with strong information about their handling, use and limitations.

I fear however the government are sitting on stocks and trying to promote correct? but prudent use for a reason, the same reason we have all the field hospitals and morgues. They know it could get worse and envisage being left without PPE.

We need to do everything we can to, where possible direct our own resources to production.
[Post edited 17 Apr 2020 10:14]


Macron must be applauded for looking after the interests of his people.

Each time I go to Bedd - au........................

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Corona Virus on 10:38 - Apr 17 with 1653 viewsHighjack

Corona Virus on 10:29 - Apr 17 by Brynmill_Jack

Macron must be applauded for looking after the interests of his people.


There’s a first time for everything.

The creatures outside looked from pig to man, and from man to pig, and from pig to man again; but already it was impossible to say which was which.
Poll: Should Dippy Drakeford do us all a massive favour and just bog off?

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