Corona Virus 22:39 - Mar 7 with 424819 views | SgorioFruit | Sorry for new thread, But how bad do you lot reckon it’s going to get here in the UK? I just been watching the news. Looking nasty in Italy. | |
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Corona Virus on 19:27 - Apr 16 with 1817 views | monmouth |
Possibly. Do you look like Steve Martin in Roxanne? | |
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Corona Virus on 19:28 - Apr 16 with 1807 views | exiledclaseboy |
Corona Virus on 19:27 - Apr 16 by monmouth | Possibly. Do you look like Steve Martin in Roxanne? |
No. Think Fred Elliott in Coronation Street. | |
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Corona Virus on 19:30 - Apr 16 with 1800 views | sainthelens |
Corona Virus on 19:27 - Apr 16 by monmouth | Possibly. Do you look like Steve Martin in Roxanne? |
Please say Ruprect in Dirty Rotten Scoundrels. | | | |
Corona Virus on 19:30 - Apr 16 with 1795 views | monmouth |
Corona Virus on 19:28 - Apr 16 by exiledclaseboy | No. Think Fred Elliott in Coronation Street. |
I’m going to have to look that up. I have a feeling it’ll improve my mood. Edit. It did. [Post edited 16 Apr 2020 19:31]
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Corona Virus on 21:00 - Apr 16 with 1722 views | waynekerr55 |
Corona Virus on 19:28 - Apr 16 by exiledclaseboy | No. Think Fred Elliott in Coronation Street. |
Ffs Clasey | |
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Corona Virus on 22:09 - Apr 16 with 1653 views | Oldjack |
Corona Virus on 18:20 - Apr 16 by raynor94 | Do you really care about football at this time? |
this is a football board ,tit | |
| Prosser the Tosser dwells on Phil's bum hole like a rusty old hemorrhoid ,fact
You Greedy Bastards Get Out Of OUR Club!
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Corona Virus on 22:35 - Apr 16 with 1607 views | Garyjack |
Corona Virus on 22:09 - Apr 16 by Oldjack | this is a football board ,tit |
Yes, but this is a thread about a virus that is killing thousands upon thousands of people worldwide, and your contribution is "The football will be fvcked"! | | | |
Corona Virus on 22:44 - Apr 16 with 1596 views | raynor94 |
Corona Virus on 22:09 - Apr 16 by Oldjack | this is a football board ,tit |
Genuinely speechless | |
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Corona Virus on 23:12 - Apr 16 with 1564 views | majorraglan | PHW did 755 tests yesterday, they have a capacity of 1300 but we should have been at 5,000 by me. Dreadful. | | | |
Corona Virus on 23:28 - Apr 16 with 1537 views | Joe_bradshaw |
Corona Virus on 22:09 - Apr 16 by Oldjack | this is a football board ,tit |
It's on the non football board ya big booby. | |
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Corona Virus on 00:49 - Apr 17 with 1482 views | longlostjack |
Corona Virus on 10:20 - Apr 16 by Professor | There are multiple genetic factors and epigenetic factors at play. The most obvious one is distribution of the differing ACE2 receptor types that the virus targets for cell entry. Typically this is a weak point of any virus in the need for a specific type of receptor which means that a population or ethnic group that may have a greater or lesser amount of the specific receptor that SARs-CoV2 uses. The specificity also means that viruses rarely species 'jump'. Secondly there will be a big immunogenetics component based on a molecule called MHC. MHC Class I molecules are on most cells and allow the immune system to recognise if a cell in cancerous or infected. Class II are on specialised cells which present antigen to receptors on host lymphocytes which lead to the generation of antibody responses. We each have 6 different class I and II molecules. The right MHC type is needed to effectively deal with a pathogen-if you have the right one in your armoury you get a better immune response. As each molecule is polymorphic we can deal with many infections (personal survival) but variation in the types in a population lead to at least some of the population being effective against any individual challenge. There will be masses of other variations in the immune system ranging on how effective cells like macrophages are at killing the virus, how well we regulate inflammation and so on. There are also non-immune factors e.g. sickle cell trait which gives more resistance to malaria, and perhaps even vitamin D (though seems unlikely) but lifestyle factors lead to non-genetic changes or epigenetic changes that can lead to marked differences in resistance-e.g. exposure to pollution, a specific diet components. I am not talking of obesity and other obvious factors, but subtle changes we don't easily see |
ACE2 Receptors. What’s your take on blood pressure medication Prof? | |
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Corona Virus on 00:53 - Apr 17 with 1479 views | longlostjack |
Corona Virus on 19:24 - Apr 16 by monmouth | Snap. My life is much the same, and I don’t have to feel any unease for not having any friends. As long as I can get food and beer and work remotely to get the money to pay for the quantity of beer I need, I can do lockdown until hell freezes over. Or strictly come dancing is allowed back on. |
Bang on! | |
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Corona Virus on 07:24 - Apr 17 with 1366 views | Highjack | That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room? | |
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Corona Virus on 07:45 - Apr 17 with 1353 views | JACKMANANDBOY |
Corona Virus on 07:24 - Apr 17 by Highjack | That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room? |
Let's see how many he can source. WHO says masks should be reserved for health workers. [Post edited 17 Apr 2020 7:50]
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Corona Virus on 07:51 - Apr 17 with 1346 views | Kilkennyjack |
Corona Virus on 07:24 - Apr 17 by Highjack | That lovely man Sadiq Khan has called for face masks to be compulsory. I think getting one for him would be an improvement. On another note has anybody ever seen Sadiq Khan and Jose Mourinho in the same room? |
No - good spot. I suspect Mr Khan knows more about attacking football though. Obviously Mr Khan is correct about the masks. The only reason for any other guidance would be to protect supply lines for the medical workers. And thats fair enough. In Tesco Fforestfach this week about 20% of people were wearing masks anyhow...? | |
| Beware of the Risen People
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Corona Virus on 07:55 - Apr 17 with 1339 views | Highjack |
Corona Virus on 07:51 - Apr 17 by Kilkennyjack | No - good spot. I suspect Mr Khan knows more about attacking football though. Obviously Mr Khan is correct about the masks. The only reason for any other guidance would be to protect supply lines for the medical workers. And thats fair enough. In Tesco Fforestfach this week about 20% of people were wearing masks anyhow...? |
Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them. Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something? | |
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Corona Virus on 08:21 - Apr 17 with 1323 views | JACKMANANDBOY |
Corona Virus on 07:55 - Apr 17 by Highjack | Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them. Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something? |
Looks like Tesco stores in Fforestfach [Post edited 17 Apr 2020 8:21]
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Corona Virus on 09:03 - Apr 17 with 1280 views | Oldjack |
Corona Virus on 23:28 - Apr 16 by Joe_bradshaw | It's on the non football board ya big booby. |
99% of people who visit this SITE are football fans | |
| Prosser the Tosser dwells on Phil's bum hole like a rusty old hemorrhoid ,fact
You Greedy Bastards Get Out Of OUR Club!
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Corona Virus on 09:42 - Apr 17 with 1251 views | JACKMANANDBOY |
Corona Virus on 09:03 - Apr 17 by Oldjack | 99% of people who visit this SITE are football fans |
The other 1 percent I'm worried about. | |
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Corona Virus on 10:12 - Apr 17 with 1223 views | chad |
Corona Virus on 07:55 - Apr 17 by Highjack | Is he correct about the masks? As it stands both the WHO and NHS advice states you shouldn’t bother with them. Also where the hell are all these people getting these masks from if the NHS can’t get them? Is there some sort of black market for them or something? |
Possibly NHS advice is based on WHO advice, which itself to me seemed primarily aimed at protecting supplies to the health service. WHO of course in mid jan notably also advised no reason for travel restrictions with China or checks on travellers; and at much the same time gave validity to the report from China saying there was no evidence of human to human transmission by tweeting it. This at a time when China was already imprisoning doctors who were trying to alert others to the dangers of infection by this virus after witnessing it themselves. WHO also only recommend a 1 metre social distance when it is well recognised that coughs and sneezes can travel much much further and create aerosols (as shown with photographic evidence in research by MIT.). As well as the potential for aerosol transmission (as per measles and several others) when it has been shown that the virus can remain infectiously viable in aerosols for at least 3 hours. Ordinary face masks (Fluid Resistant Surgical Masks) do not protect the eyes and are not fine enough to prevent the virus from entering in aerosol but can prevent the main droplet path and is believed can deflect air flows containing the virus so can afford a degree of protection. Their multilayered construct also affords some protection. Most importantly given the wide spread of this virus, the ability to infect others from the high viral load in the throat which exists at early stages and potential for low / no symptoms at these early stages, then we should welcome others wearing them as they suppress droplets (accepted by WHO as primary cause of transmission) both from coughing/sneezing and talking/breathing Screwfix used to stock a good selection of disposable and reusable P3 masks (that will stop the virus with a high degree of efficiency if fitted properly) but I understand they (rightfully) diverted all their stocks for care workers when this flared up. But any significant face covering can afford some degree of protection especially against you spreading it. I have no idea where people are getting their masks from, some will have some from DIY as do I. I know even in the early stages there were reports of thousands being stolen from French hospitals. Our NHS also reportedly had a large order with a French company, as one of their initial clients, but Macron forced them to cancel it when he decided to retain all their masks and mask production for France. My personal opinion, once hospitals, care homes and service providers catered for we need to roll them out widely with strong information about their handling, use and limitations. I fear however the government are sitting on stocks and trying to promote correct? but prudent use for a reason, the same reason we have all the field hospitals and morgues. They know it could get worse and envisage being left without PPE. We need to do everything we can to, where possible direct our own resources to production. [Post edited 17 Apr 2020 10:14]
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Corona Virus on 10:16 - Apr 17 with 1209 views | Professor |
Corona Virus on 00:49 - Apr 17 by longlostjack | ACE2 Receptors. What’s your take on blood pressure medication Prof? |
No idea sorry. There seems to be increased prevalence in metabolic diseases and obesity which could also be related to medication for blood pressure, but that is just speculation on my part. One thing that may come out retrospectively I guess | | | |
Corona Virus on 10:18 - Apr 17 with 1207 views | chad |
Corona Virus on 19:28 - Apr 16 by exiledclaseboy | No. Think Fred Elliott in Coronation Street. |
‘No. Think Fred Elliott in Coronation Street.’ I said Think Fred Elliott in Coronation Street. There fixed that for you ;) | | | |
Corona Virus on 10:29 - Apr 17 with 1189 views | Brynmill_Jack |
Corona Virus on 10:12 - Apr 17 by chad | Possibly NHS advice is based on WHO advice, which itself to me seemed primarily aimed at protecting supplies to the health service. WHO of course in mid jan notably also advised no reason for travel restrictions with China or checks on travellers; and at much the same time gave validity to the report from China saying there was no evidence of human to human transmission by tweeting it. This at a time when China was already imprisoning doctors who were trying to alert others to the dangers of infection by this virus after witnessing it themselves. WHO also only recommend a 1 metre social distance when it is well recognised that coughs and sneezes can travel much much further and create aerosols (as shown with photographic evidence in research by MIT.). As well as the potential for aerosol transmission (as per measles and several others) when it has been shown that the virus can remain infectiously viable in aerosols for at least 3 hours. Ordinary face masks (Fluid Resistant Surgical Masks) do not protect the eyes and are not fine enough to prevent the virus from entering in aerosol but can prevent the main droplet path and is believed can deflect air flows containing the virus so can afford a degree of protection. Their multilayered construct also affords some protection. Most importantly given the wide spread of this virus, the ability to infect others from the high viral load in the throat which exists at early stages and potential for low / no symptoms at these early stages, then we should welcome others wearing them as they suppress droplets (accepted by WHO as primary cause of transmission) both from coughing/sneezing and talking/breathing Screwfix used to stock a good selection of disposable and reusable P3 masks (that will stop the virus with a high degree of efficiency if fitted properly) but I understand they (rightfully) diverted all their stocks for care workers when this flared up. But any significant face covering can afford some degree of protection especially against you spreading it. I have no idea where people are getting their masks from, some will have some from DIY as do I. I know even in the early stages there were reports of thousands being stolen from French hospitals. Our NHS also reportedly had a large order with a French company, as one of their initial clients, but Macron forced them to cancel it when he decided to retain all their masks and mask production for France. My personal opinion, once hospitals, care homes and service providers catered for we need to roll them out widely with strong information about their handling, use and limitations. I fear however the government are sitting on stocks and trying to promote correct? but prudent use for a reason, the same reason we have all the field hospitals and morgues. They know it could get worse and envisage being left without PPE. We need to do everything we can to, where possible direct our own resources to production. [Post edited 17 Apr 2020 10:14]
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Macron must be applauded for looking after the interests of his people. | |
| Each time I go to Bedd - au........................ |
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Corona Virus on 10:38 - Apr 17 with 1653 views | Highjack |
Corona Virus on 10:29 - Apr 17 by Brynmill_Jack | Macron must be applauded for looking after the interests of his people. |
There’s a first time for everything. | |
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